The study was aimed to evaluate the performance of a newly developed non-invasive and non-contact bilirubin measurement device (AJO-Neo) as an alternative to the conventional invasive biochemical method of total serum bilirubin (TSB) estimation in preterm and term neonates suffering from hyperbilirubinemia associated with risk factors, and/or undergoing phototherapy. This contribution is an extension of the Intelligent Sensors and Monitoring System for Low-cost Phototherapy Light for Jaundice Treatment that was presented in the International Symposium on Multimedia and Communication Technology (ISMAC) in 2019. Its solar-power features for off-grid and remote deployments were also explored. The system is envisioned to be integrated with Mobile or Near Cloud as part of Smart Nursing Station together with other hospital equipment for monitoring, collection, and management of medical records and services.
Developing this tool will help determine the intensity of yellowish color in infants and can monitor NNJ in a non-invasive way. This paper showcases our previous and continuously improving development at Ateneo Innovation Center (AIC) and partners in designing and further enhancing the existing Low-cost Phototherapy Light System (LPLS) and Improved Low-cost Phototherapy Light System (ILPLS) to the new Smart Low-cost Phototherapy Light System (Smart LPLS) with non-invasive jaundice monitoring for newborns with Neonatal Jaundice (NNJ).
Amadine yaounde skin#
Only a few studies have analyzed their accuracy in multiethnic populations, but none has used a validated neonatal skin color scale.Jaundice meters are extensively used to diagnose neonatal hyperbilirubinemia, although controversies exist on their reliability depending on skin color.This may help reduce the number of blood samples for newborns. Conclusions: Our study not only supports the reliability of TcB to assess SB regardless of skin color, but also supports the fact that TcB tends to overestimate SB in a higher degree in dark-skinned neonates. Bland-Altman plots showed different mean bias depending on skin color. Correlation between TcB and serum bilirubin was very good (R2 = 0.908–0.956), globally and by color group, with slight differences between darker and lighter skin colors. We obtained data from 1359 newborns (color 1 337, color 2 750, color 3 249, color 4 23) and analyzed 1549 dyads SB/TcB. With the blood sample routinely obtained at 48–72 h for the screening of inborn errors of metabolism, we determined SB and TcB with a jaundice meter. We conducted a prospective, observational study comparing SB and TcB among different skin colors. We aimed to determine the reliability of transcutaneous bilirubin in a multiethnic population based on skin color according to our neonatal skin color scale.
Ethnic classification does not correlate well with skin tone. However, its reliability depending on skin tone is still controversial. Measurement of transcutaneous bilirubin (TcB) is widely used to estimate serum bilirubin (SB). In conclusion, JAISY provides accurate and reproducible information on low to moderately high bilirubin levels in newborn infants born near-term or at term. The coefficient of variation for repeated bilirubin measurements was 8.8% for JAISY and 8.0% for JM105 ( p = 0.79). The correlations remained after stratifying the data by gestational age, postnatal age and skin color. There was a high degree of agreement with significant correlations between bilirubin values measured with the two devices on the forehead (Pearson’s r = 0.94, p < 0.001) and the chest (r = 0.94, p < 0.001). The bilirubin values varied between 0 and 320 µmol/l (0–18.8 mg/dl). In each infant, the mean of three repeated measurements in the forehead was calculated for each instrument, followed by a similar measurement on the chest. For this purpose, 930 bilirubin measurements were performed in 141 newborn infants born near-term or at term (gestational age 35–41 weeks postnatal age 1–6 days 71 boys including 29 infants with darker skin) and compared to those of a previously validated instrument (JM105). The objective of this study was to evaluate a new transcutaneous bilirubinometer (JAISY). To avoid brain damage in newborn infants, effective tools for prevention of excessive neonatal hyperbilirubinemia are needed.
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